Zenas is a clinical-stage global biopharmaceutical company committed to becoming a leader in the development and commercialization of transformative therapies for patients with autoimmune diseases. Our core business strategy combines our experienced leadership team with a disciplined product candidate acquisition approach to identify, acquire and develop product candidates globally that we believe can provide superior clinical benefits to patients living with autoimmune diseases. Zenas is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, Zenas’ lead product candidate, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb, which are broadly present across B cell lineage, to inhibit the activity of cells that are implicated in many autoimmune diseases without depleting them. We believe that obexelimab’s unique mechanism of action and self-administered, subcutaneous injection regimen may broadly and effectively address the pathogenic role of B cell lineage in chronic autoimmune disease. Orelabrutinib is a potentially best-in-class, highly selective CNS-penetrant, oral, small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with the potential to address compartmentalized inflammation and disease progression in Multiple Sclerosis (MS). Zenas’ earlier stage programs include ZB021, a clinical-stage, potentially best-in-class, oral, IL-17AA/AF inhibitor; ZB022, a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor; and ZB014, a preclinical half-life extended anti-CD-19 and FcγRIIb monoclonal antibody.

We are seeking top talent who share our commitment to patients and have a track record of success in acquiring, developing and commercializing products across the globe. Our colleagues have an opportunity to engage in a fast-paced learning environment and experience individual and organizational success as we work towards becoming a global immunology and autoimmune disease leader, while living our values of Transparency, Relationships, Urgency, Excellence and Innovation – TRUE Innovation!

Position Summary:

Zenas BioPharma is looking for a Director of Global Compliance to play a central role in shaping and advancing our global ethics and compliance program as we move toward commercial launch. This is a high-impact, highly visible role that sits at the intersection of compliance, business partnership, and organizational culture.

Reporting to the Executive Director, Global Compliance, you will help design, implement, and mature scalable compliance solutions that support Zenas's growing commercial and medical organizations — ensuring we meet evolving regulatory obligations while fostering a culture of integrity, accountability, and transparency. You will work closely with cross-functional partners across Legal, Medical Affairs, Commercial, Finance, HR, and IT to ensure our compliance program is practical, well-integrated, and fit for purpose.

If you are a collaborative, solutions-oriented compliance professional who thrives in a fast-paced environment and is energized by building programs that matter — this role is for you.

Key Responsibilities

Program Development & Governance

Support the build and continuous improvement of Zenas's global ethics and compliance program, ensuring alignment with organizational values, applicable laws, regulations, and industry codes
Conduct and maintain periodic compliance risk assessments to identify, prioritize, and mitigate emerging risks
Monitor changes in applicable laws, regulations, and industry guidance and translate them into actionable program updates

Policies & Written Standards

Draft, implement, and maintain compliance-related policies and procedures, including the effective rollouts across the organization
Ensure policies are clear, practical, and aligned to the needs of a growing, commercially oriented organization

Training & Education

Develop and deliver compliance training programs and awareness communications for employees and key stakeholders, with emphasis on field-based roles