For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases.

Our commercial portfolio includes treatments for hypercortisolism and oncology, and the company has discovered more than 1,000 proprietary selective cortisol modulators and glucocorticoid receptor antagonists. With advanced clinical trials in patients with hypercortisolism, solid tumors, ALS and liver disease, Corcept is unlocking the power of cortisol modulation to help address some of the most devastating diseases patients face today.

Corcept is headquartered in Redwood City, California. To learn more, visit www.corcept.com.

Reporting to the Vice President, Head of Patient Safety & Pharmacovigilance, this role will be responsible for leading the Medical Safety Physician function, ensuring the quality, consistency, and medical integrity of safety assessments across the portfolio. The individual will provide oversight of medical review, signal evaluation, and benefit–risk assessments across clinical development and post-marketing programs.

Operate as a peer functional leader alongside the Head of Safety Science, Head of Safety Operations, and QPPV(s) within the Patient Safety & Pharmacovigilance organization, partnering to provide strategic leadership, ensure effective governance, and maintain an integrated approach to patient safety and pharmacovigilance across the portfolio
Partner with key internal stakeholders, including Clinical Development and Medical Affairs to ensure alignment of safety insights across the product lifecycle while maintaining independent medical judgment on safety and benefit–risk decisions

Responsibilities

Medical Safety Leadership

Define and drive the medical safety strategy across the portfolio
Provide senior medical safety leadership for safety interpretation and benefit–risk assessment
Ensure consistent medical oversight of clinical and post-marketing safety activities

Team Leadership

Lead, build, and develop a team of Medical Safety Physicians
Set standards for medical review quality and consistency
Scale the organization to support portfolio and geographic growth

Safety Review & Surveillance

Lead medical evaluation of safety signals in partnership with Safety Science
Ensure robust benefit–risk assessment across programs
Integrate clinical interpretation into safety surveillance outputs

Key Collaboration

Partner with Clinical Development to integrate safety into development strategy
Partner with Medical Affairs to ensure consistent safety messaging
Provide medical interpretation and benefit–risk input to cross-functional decisions

Regulatory & Governance

Oversee medical input into DSURs, PADERs, and regulatory safety submissions
Support health authority interactions and safety queries
Contribute to cross-functional safety governance forums, providing medical expertise and benefit–risk input in cross-functional safety governance forums

Risk Management

Identify and escalate safety risks at product and portfolio level
Define medical risk mitigation strategies with cross-functional partners
Drive continuous improvement in medical safety processes and standards

Preferred Skills, Qualifications and Technical Proficiencies

MD required; board certification in a relevant specialty strongly preferred
12+ years of progressive leadership experience in the pharmaceutical or biotechnology industry, including significant experience in Medical Safety and pharmacovigilance; oncology experience required
Demonstrated success leading Medical Safety organizations and managing teams of Medical Safety Physicians
Deep expertise in safety signal management, medical review, aggregate safety assessment, and benefit–risk evaluation across clinical development and post-marketing products
Extensive experience interacting with global health authorities and leading safety-related regulatory activities
Strong understanding of global pharmacovigilance regulations and industry best practices
Proven ability to influence cross-functional and executive-level decision-making and build effective partnerships across Patient Safety/Pharmacovigilance, Clinical Development, Regulatory Affairs, Medical Affairs and Biometrics