Each of us cares about someone who will need medicines. That’s why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients that need them. We pursue truth and scientific rigour and have the courage to work at the edge of the unknown.

We are seeking an experienced Senior Clinical Scientist to join our growing Clinical Development team, to drive early-phase development in oncology and endocrinology indications. Reporting to VP of Clinical Development and in collaboration with a Medical Director, you will integrate preclinical findings into clinical strategies and design Phase 1-2 clinical trials, author clinical study protocols and regulatory filings (INDs and CTAs) to advance novel drug candidates into clinic, execute early phase studies, and deliver proof-of-concept.

How you might spend your days

Study design and strategy: evaluating preclinical data and scientific concepts to develop clinical study Protocols, Investigator’s Brochures (IBs), Informed Consent Forms (ICFs) for Phase 1–2 dose escalation and expansion studies
Regulatory submissions: authoring clinical sections for global IND and CTA submissions, responding to inquiries from health authorities (FDA, EMA, HC), preparing protocol amendments, and contributing to Clinical Study Reports (CSRs)
Medical monitoring and patient safety oversight: supporting the Medical Director with medical monitoring and data review activities, evaluating safety, efficacy, PK and PD trends, and preparing and presenting data at Safety Monitoring Committee (SMC) meetings to drive dose decisions
Cross-functional leadership & integration: acting as the Clinical Development liaison across the organization, collaborating with:
Translational Science: integrating preclinical scientific findings, pharmacokinetic (PK) and biomarker strategies into clinical trial design
Biometrics and Data Management: partnering with the study statistician to develop optimal innovative study designs, contributing to data delivery, review, and interpretation to drive conclusions for proof-of-concept
Regulatory Affairs: aligning clinical strategies with global regulatory requirements and supporting briefing document development for agency interactions
Clinical Operations: ensuring that clinical protocols are scientifically sound and operationally feasible; providing clinical site and investigator support throughout the study cycle
Quality Assurance: ensuring that all clinical activities and documentation strictly adhere to GCP/ICH standards and are inspection ready
External engagement: Engaging with medical experts and study investigators throughout the study cycle, contributing to advisory boards to refine clinical strategy and discuss study outcomes

We’d love to hear from you if

You have an advanced scientific degree (Ph.D., PharmD, M.S. in Life Sciences, or equivalent; MD welcomed)
You have 5+ years of experience in biopharmaceutical clinical development, with at least 1 year dedicated to early-phase (Phase 1–2) clinical trials
You have a demonstrated background in Oncology or Endocrinology/Metabolic diseases
You have knowledge of GCP, ICH guidelines, clinical trial design, medical monitoring, data review, dose-finding strategies, PK and PD assessments
You have strong problem-solving skills, able to navigate complex operational and scientific challenges

What we offer

AbCellera’s hiring range for this role is CAD $120,000 - $152,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.

You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find a strong sense of community and connections across AbCellera through our work, clubs, and socials.

About AbCellera

Creating medicines is the most important work we can do.