Who We Are:

Xenon Pharmaceuticals (NASDAQ:XENE) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team.

What We Do:

We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we submitted a New Drug Application to the Food and Drug Administration in the third quarter of 2026. Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial. In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN1701 and XEN1720 (targeting Nav1.7) and XEN1120 (targeting Kv7), which are being developed for pain. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations.

About the Role:

To be successful in this role, you will bring strong scientific acumen and a passion for adult learning, translating complex clinical and mechanistic concepts into clear, practical learning experiences. You will partner closely with Medical Directors and cross-functional stakeholders to develop and maintain KIQs, core talking points, objection-handling resources, and other enablement tools, and lead onboarding and ongoing medical training for new hires and existing teams. You will also help translate scientific literature and field insights into training priorities and actionable medical initiatives, contributing to integrated medical planning within your areas of responsibility. You will also support the Medical Directors in congress execution, training, insights-to-action, tiering, and literature alerts. Reporting directly to the Executive Director, Medical Affairs, you will work within a multidisciplinary team, interfacing with Field Medical, Clinical Development, Scientific Communications, Commercial, Legal, Regulatory, and Compliance to ensure scientific accuracy, alignment, and high-quality execution.

This position is based out of Boston, MA, USA in our Needham office. We will consider remote locations for exceptional candidates. If in the Boston area, we require a minimum of 2 days per week in the office.

Responsibilities

Medical Training Strategy: As the primary focus of the role, own the end-to-end medical and scientific training development, and delivery across disease states and the neuroscience portfolio (e.g., epilepsy, MDD, bipolar depression, pain), aligning curricula with program milestones, evidence generation, evolving scientific communications, and identified learning needs.

Training Module Development: Design and develop engaging training modules for different audiences and use-cases (field medical, congress teams, cross-functional partners), incorporating adult learning principles, knowledge checks, and practical application exercises.