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Genesis Molecular AI

Product Software Engineer (Senior / Staff)

San Mateo, CA; New York, NYHybrid · United States
Staff · FullTime · AI
POSTED 12 OCTVERIFIED 1D AGO
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Role
28 days opentrue age
Posted 12 Oct
Pay
$205k–$284kno pay posted
Market p25–p75
$205k–$284k
SF Bay Area · n=969 · 365d to 6 Nov
CompanyGenesis Molecular AI →
10open roles
Opened · 30d
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Closed · 30d
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3d of snapshots · 30d window
Market
9,268open · Staff Software engineering
Opened · 7d
+5106% of open
All software engineering
75,188open
All tracked boards · live 10 Nov · n=9,268
Visa
3H-1B LCAs · FY26
Median wage
$214k
LCAs FY26 · n=3 · to 2026-05-18

Product Software Engineer (Senior / Staff)

Genesis Molecular AI is building a world-class software team to solve problems in drug discovery through machine learning, biophysical simulation, and computational chemistry. We are looking for engineers excited to help develop new medicines and play a critical role in building out our software platform.

You will

Own and evolve the full-stack platform that computational chemists use daily, from data exploration and experiment management to real-time visualization, shipping AI-native workflows and modern interaction patterns that shorten the loop between hypothesis and insight

Build tools for exploring and visualizing high-dimensional datasets containing molecules, proteins, and ML model predictions

Design flexible systems for running complex chemical workflows incorporating different computational chemistry tools and ML models

Partner with machine learning engineers and computational chemists to develop and productionize new computational methods for molecular property prediction

Scale our data infrastructure to handle billions of datapoints and thousands of parallel deep learning and molecular dynamics jobs

You are

A deep thinker who reasons from first principles, balances attention to detail with architectural thinking, and has an investigative curiosity to find the root cause of a problem

Comfortable owning problems across the entire stack — frontend interfaces, backend services, data pipelines, and infrastructure

Experienced shipping production code and driving projects end-to-end with minimal hand-holding

Motivated by working closely with users to understand their problems and design simple solutions

Excited to work at the intersection of software engineering, drug discovery, and machine learning

What we offer

The opportunity to work on high impact tools and products that are immediately deployed to accelerate the discovery of new medicines

Strong technical coworkers in AI, software, and chemistry, who all have a powerful mix of intellectual curiosity and humility. The team reads and discusses 1-2 machine learning or chemistry papers every week to stay on top of the field and inspire new ideas

Competitive salary and equity. Medical, dental, and vision insurance, and a 401(k) program

About Genesis Molecular AI

Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. Our generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis is backed by premier AI and life science investors, including a16z, NVIDIA, Rock Springs Capital, Menlo Ventures, T. Rowe Price, Fidelity, and Radical Ventures. Genesis has also signed category-leading AI-pharma deals, the most recent of which was a significant expansion with Incyte (see coverage in Forbes and GEN) with a total potential deal value of several billion dollars.

Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.

Source · Genesis Molecular AIFirst seen 2 NovOriginal ↗